Is Ethyl Beta-Naphthyl Ether safe in cosmetics?
Ethyl Beta-Naphthyl Ether has a safety rating of "POOR" in our database. EU status: prohibited. US status: restricted.
POOR
Cosmetic Ingredient
Ethyl Beta-Naphthyl Ether
Also known as: Bromelia, Nerolin, Naphthalene, 2-ethoxy-, Ethyl 2-naphthyl ether, 4-06-00-04257 (+12 more)
INCI: ETHYL BETA-NAPHTHYL ETHER
Ethyl Beta-Naphthyl Ether (CAS 93-18-5) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient. NOAEL 5 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
Cross-Vertical Regulatory Divergence
Ethyl Beta-Naphthyl Ether is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H411).
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
Function
Fragrance ingredient
Editorial assessment
POOR
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
2-ethoxynaphthalene
InChIKey
GUMOJENFFHZAFP-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
restricted
US Notes
Not specifically restricted under 21 CFR 700 — permitted under general safety obligation
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ethyl Beta-Naphthyl Ether.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Ethyl Beta-Naphthyl Ether across SCCS product categories, with measured dermal absorption where available.
HRIPT Human Patch Test Studies
2 human repeat insult patch tests aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 1296 | - | - |
| HRIPT | - | 0 | - | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (5)
JECFA Number
1258
Source: WHO/JECFA
JECFA Evaluation
2-ETHOXYNAPHTHALENE | 2003 | No safety concern at current levels of intake when used as a flavouring agent | TRS 922-JECFA 61/86 | FAS 52-JECFA 61/335
Source: WHO/JECFA
JECFA Evaluation
NEROLIN BROMELIA | 2003 | No safety concern at current levels of intake when used as a flavouring agent | TRS 922-JECFA 61/86 | FAS 52-JECFA 61/335
Source: WHO/JECFA
JECFA Evaluation
beta-NAPHTHYL ETHYL ETHER | 2003 | No safety concern at current levels of intake when used as a flavouring agent | TRS 922-JECFA 61/86 | FAS 52-JECFA 61/335
Source: WHO/JECFA
JECFA Evaluation
ETHYL 2-NAPHTHYL ETHER | 2003 | No safety concern at current levels of intake when used as a flavouring agent | TRS 922-JECFA 61/86 | FAS 52-JECFA 61/335
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (4)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Editorial summary
Preliminary editorial summary for Ethyl Beta-Naphthyl Ether — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
fragrance-component
epa_safer_alternative
ifra_fragrance
fda_food_additive
Known Synonyms
Bromelia
Nerolin
Naphthalene, 2-ethoxy-
Ethyl 2-naphthyl ether
4-06-00-04257
BRN 2042397
EINECS 202-226-7
Ethyl beta-naphtholate
FEMA No. 2768
beta-Naphthol ethyl ether
2-Naphthol ethyl ether
beta-Naphthyl ethyl ether
Nerolin II
Nerolin new
Neroline
NSC 1319
UNII-ZF3IS6G3R7
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
SCIL (9/2019)
fracking; water
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
BETA-NAPHTHYL ETHYL ETHER
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Ethyl Beta-Naphthyl Ether allowed in the EU?
Ethyl Beta-Naphthyl Ether EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl Beta-Naphthyl Ether do in cosmetics?
Ethyl Beta-Naphthyl Ether functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 93-18-5.
Is Ethyl Beta-Naphthyl Ether used outside cosmetics?
Ethyl Beta-Naphthyl Ether also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Ethyl Beta-Naphthyl Ether have different safety status in cosmetics vs industrial chemicals?
Ethyl Beta-Naphthyl Ether is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H411).
Compliance Tools
Check Ethyl Beta-Naphthyl Ether compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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