Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
7 study endpoints found for Ethyl Beta-Naphthyl Ether. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 5 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 5 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 5.1 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 5 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 125 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 20 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Naphthyl ethers are linked to leukoderma and depigmentation. Parent compound beta-naphthol is EU Annex II prohibited. Use in cosmetics is not advisable without a full toxicological dossier and confirmation of Annex II status.
Regulatory Flags
Frequently Asked Questions
Is Ethyl Beta-Naphthyl Ether safe in cosmetics?
Naphthyl ethers are linked to leukoderma and depigmentation. Parent compound beta-naphthol is EU Annex II prohibited. Use in cosmetics is not advisable without a full toxicological dossier and confirmation of Annex II status. The EU classifies Ethyl Beta-Naphthyl Ether as "prohibited". Safety rating: POOR. 7 toxicological study endpoint(s) are available in our database.
Is Ethyl Beta-Naphthyl Ether allowed in the EU?
Ethyl Beta-Naphthyl Ether EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl Beta-Naphthyl Ether do in cosmetics?
Ethyl Beta-Naphthyl Ether functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 93-18-5.
What is the Margin of Safety for Ethyl Beta-Naphthyl Ether?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Ethyl Beta-Naphthyl Ether?
The NOAEL (No Observed Adverse Effect Level) for Ethyl Beta-Naphthyl Ether is 5 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 7 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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