Ethyl Urocanate

INCI: ETHYL UROCANATE

CAS Number
27538-35-8
Function
UV Absorber / Skin Conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not listed on FDA OTC Sunscreen Monograph; no GRASE classification for sunscreen use.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Ethyl Urocanate is a UV absorber not included in EU Annex VI; the parent compound's cis-isomer is an established immunosuppressant with photocarcinogenesis links, and no dermal absorption or safety data exist for this specific compound.

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Concern Level: High

Regulatory Flags

uv-absorber skin-conditioning no-sccs-opinion no-annex-vi immunosuppression-risk photocarcinogenesis-concern data-gap high-concern

Frequently Asked Questions

Is Ethyl Urocanate safe in cosmetics?

Ethyl Urocanate is a UV absorber not included in EU Annex VI; the parent compound's cis-isomer is an established immunosuppressant with photocarcinogenesis links, and no dermal absorption or safety data exist for this specific compound. The EU classifies Ethyl Urocanate as "permitted". Safety rating: POOR.

Is Ethyl Urocanate allowed in the EU?

Ethyl Urocanate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethyl Urocanate do in cosmetics?

Ethyl Urocanate functions as: UV Absorber / Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 27538-35-8.

What is the Margin of Safety for Ethyl Urocanate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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