Hexapeptide-40 Methionyl SH-Polypeptide-11
INCI: HEXAPEPTIDE-40 METHIONYL SH-POLYPEPTIDE-11
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
High data gap. Novel fusion peptide with SH-prefix indicating synthetic human-identical sequence produced via biotech (e.g., plant expression systems). Requires complete supplier toxicology package including genotoxicity, sensitization (DPRA/KeratinoSens), and irritation studies. Methionine residue susceptible to oxidation—verify stability data.
Regulatory Flags
Frequently Asked Questions
Is Hexapeptide-40 Methionyl SH-Polypeptide-11 safe in cosmetics?
High data gap. Novel fusion peptide with SH-prefix indicating synthetic human-identical sequence produced via biotech (e.g., plant expression systems). Requires complete supplier toxicology package including genotoxicity, sensitization (DPRA/KeratinoSens), and irritation studies. Methionine residue susceptible to oxidation—verify stability data. The EU classifies Hexapeptide-40 Methionyl SH-Polypeptide-11 as "permitted". Safety rating: POOR.
Is Hexapeptide-40 Methionyl SH-Polypeptide-11 allowed in the EU?
Hexapeptide-40 Methionyl SH-Polypeptide-11 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexapeptide-40 Methionyl SH-Polypeptide-11 do in cosmetics?
Hexapeptide-40 Methionyl SH-Polypeptide-11 functions as: Skin conditioning (biotech-derived fusion peptide). It is classified as a cosmetic ingredient in our database. CAS number: Not publicly available.
What is the Margin of Safety for Hexapeptide-40 Methionyl SH-Polypeptide-11?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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