Is Hexylene Glycol safe in cosmetics?
Hexylene Glycol has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
GOOD
Cosmetic Ingredient
Hexylene Glycol
INCI: HEXYLENE GLYCOL
Hexylene Glycol (CAS 107-41-5) is a cosmetic cosmetic ingredient functioning as solvent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
Function
solvent
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No FDA pre-market approval required for cosmetic use. Indirect food additive (IFA) status as defoaming agent under 21 CFR 176.210. No cosmetic-specific restrictions. EPA Safer Chemical Program classifies 2-Methyl-2,4-pentanediol as expected to be of low concern. CIR Expert Panel has concluded safe as presently used.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexylene Glycol.
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for Hexylene Glycol — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
eu-unrestricted
cir-approved
no-sccs-opinion
eu_children_restricted
epa_safer_alternative
ifra_fragrance
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
HEXYLENE GLYCOL
ChEMBL ID
CHEMBL2104293
Max Phase
-1
Frequently Asked Questions
Is Hexylene Glycol allowed in the EU?
Hexylene Glycol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexylene Glycol do in cosmetics?
Hexylene Glycol functions as: solvent. It is classified as a cosmetic ingredient in our database. CAS number: 107-41-5.
Is Hexylene Glycol used outside cosmetics?
Hexylene Glycol also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Hexylene Glycol compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Is Hexylene Glycol in Your Products?
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Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Hexylene Glycol in your formulation.