Poor Cosmetic Ingredient

Hydrolyzed Cow Placenta Extract

INCI: HYDROLYZED COW PLACENTA EXTRACT

CAS Number
Not specifically assigned
Function
Skin conditioning
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes Permitted but CIR concluded insufficient data to support safety (2002). Requires skin sensitization testing at use concentration, gross pathology and histopathology from repeated exposure, dermal reproductive and developmental toxicity studies, photosensitization testing, genotoxicity in mammalian system, and ocular toxicity assessment.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Prohibited in EU due to CIR insufficient data finding (2002), BSE/TSE prion risk from bovine-sourced material, potential estrogenic hormonal activity, and restrictions in Japan and some ASEAN markets despite US permission.

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Concern Level: High

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Hydrolyzed Cow Placenta Extract safe in cosmetics?

Prohibited in EU due to CIR insufficient data finding (2002), BSE/TSE prion risk from bovine-sourced material, potential estrogenic hormonal activity, and restrictions in Japan and some ASEAN markets despite US permission. The EU classifies Hydrolyzed Cow Placenta Extract as "prohibited". Safety rating: POOR.

Is Hydrolyzed Cow Placenta Extract allowed in the EU?

Hydrolyzed Cow Placenta Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Cow Placenta Extract do in cosmetics?

Hydrolyzed Cow Placenta Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned.

What is the Margin of Safety for Hydrolyzed Cow Placenta Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Hydrolyzed Cow Placenta Extract compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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