Regulatory Status
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Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Linalyl Isobutyrate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 1000 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 1000 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
Metabolizes to linalool and isobutyric acid; linalool is a known fragrance allergen requiring label declaration above 0.001% (leave-on) or 0.01% (rinse-off) in the EU. Ecotoxicity rated as "Toxic" by Givaudan's environmental profile.. Colorless liquid with a natural, fresh lavender-bergamot character; use level 0.5-5%; readily biodegradable; tenacity on blotter ~7 hours.
Regulatory Flags
Frequently Asked Questions
Is Linalyl Isobutyrate safe in cosmetics?
Metabolizes to linalool and isobutyric acid; linalool is a known fragrance allergen requiring label declaration above 0.001% (leave-on) or 0.01% (rinse-off) in the EU. Ecotoxicity rated as "Toxic" by Givaudan's environmental profile.. Colorless liquid with a natural, fresh lavender-bergamot character; use level 0.5-5%; readily biodegradable; tenacity on blotter ~7 hours. The EU classifies Linalyl Isobutyrate as "restricted". Safety rating: MODERATE. 4 toxicological study endpoint(s) are available in our database.
Is Linalyl Isobutyrate allowed in the EU?
Linalyl Isobutyrate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Linalyl Isobutyrate do in cosmetics?
Linalyl Isobutyrate functions as: Perfuming / Fragrance - enhances the top note of compositions, especially lavender, cologne, and fruity blends. It is classified as a cosmetic ingredient in our database. CAS number: 78-35-3.
What is the Margin of Safety for Linalyl Isobutyrate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Linalyl Isobutyrate?
The NOAEL (No Observed Adverse Effect Level) for Linalyl Isobutyrate is 1000 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 4 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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