Regulatory Status
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Safety Data
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Expert Verdict
Critical data gap. Synthetic ester combining lupeol with isonicotinic acid (a pyridine-4-carboxylic acid, structurally related to isoniazid). No published dermal toxicity, sensitization, or genotoxicity data. The isonicotinic acid moiety raises questions about potential hydrolysis products and systemic effects. A CPSR Assessor would flag this for full toxicological profiling before approval.
Regulatory Flags
Frequently Asked Questions
Is Lupeyl Isonicotinate safe in cosmetics?
Critical data gap. Synthetic ester combining lupeol with isonicotinic acid (a pyridine-4-carboxylic acid, structurally related to isoniazid). No published dermal toxicity, sensitization, or genotoxicity data. The isonicotinic acid moiety raises questions about potential hydrolysis products and systemic effects. A CPSR Assessor would flag this for full toxicological profiling before approval. The EU classifies Lupeyl Isonicotinate as "permitted". Safety rating: POOR.
Is Lupeyl Isonicotinate allowed in the EU?
Lupeyl Isonicotinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Lupeyl Isonicotinate do in cosmetics?
Lupeyl Isonicotinate functions as: Skin conditioning (ester of Lupeol and isonicotinic acid). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned [^1_10].
What is the Margin of Safety for Lupeyl Isonicotinate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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