Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Luteolin is a naturally occurring flavone with potent anti-inflammatory and antioxidant properties permitted in EU and US, but a critical regulatory gap exists regarding in vitro genotoxicity concerns including DNA damage and mutagenicity in Salmonella testing.
Regulatory Flags
Frequently Asked Questions
Is Luteolin safe in cosmetics?
Luteolin is a naturally occurring flavone with potent anti-inflammatory and antioxidant properties permitted in EU and US, but a critical regulatory gap exists regarding in vitro genotoxicity concerns including DNA damage and mutagenicity in Salmonella testing. The EU classifies Luteolin as "permitted". Safety rating: MODERATE.
Is Luteolin allowed in the EU?
Luteolin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Luteolin do in cosmetics?
Luteolin functions as: Skin Conditioning, Antioxidant, Anti-Inflammatory. It is classified as a Antioxidant in our database. CAS number: 491-70-3.
What is the Margin of Safety for Luteolin?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Luteolin compliance across multiple jurisdictions:
Related Ingredients
Is Luteolin in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Luteolin in your formulation.