Is Matrixyl 3000 safe in cosmetics?
Matrixyl 3000 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Matrixyl 3000
Also known as: UNII-Q41S464P1R, l-Arginine, N-(1-oxohexadecyl)glycyl-l-glutaminyl-l-prolyl-, N-Palmitoylrigin, Palmitoyl-GQPR
INCI: MATRIXYL 3000
Matrixyl 3000 (CAS 221227-05-0) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent - miscellaneous. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 221227-05-0 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning agent - miscellaneous
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR Expert Panel has concluded these ingredients safe as used.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Matrixyl 3000.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
2 property records from structured ingredient metadata.
regulatory
{"eu_status": "allowed", "us_status": "allowed"}
skin_suitability
{"oily_skin": "acceptable", "dry_skin": "recommended", "sensitive_skin": "acceptable", "combination_skin": "acceptable", "normal_skin": "recommended", "acne_prone": "acceptable", "rosacea": "acceptable", "eczema": "acceptable", "hyperpigmentation": "acceptable", "aging_mature": "recommended", "dehydrated": "recommended", "skin_benefit_primary": "anti-aging", "skin_benefit_secondary": "collagen-boo…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Matrixyl 3000.
Known Synonyms
UNII-Q41S464P1R
l-Arginine, N-(1-oxohexadecyl)glycyl-l-glutaminyl-l-prolyl-
N-Palmitoylrigin
Palmitoyl-GQPR
Chemical Function
Softener and conditioner
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Canada; pharmaceutical
Frequently Asked Questions
Is Matrixyl 3000 allowed in the EU?
Matrixyl 3000 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Matrixyl 3000 do in cosmetics?
Matrixyl 3000 functions as: Skin conditioning agent - miscellaneous. It is classified as a cosmetic ingredient in our database. CAS number: 221227-05-0.
Compliance Tools
Check Matrixyl 3000 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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