Is Methyl Beta-Cyclodextrin safe in cosmetics?
Methyl Beta-Cyclodextrin has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Methyl Beta-Cyclodextrin
Also known as: beta-Cyclodextrin, methyl ethers, O-Methyl-beta-cyclodextrin (1.8 methyls per saccharide)
INCI: METHYL BETA-CYCLODEXTRIN
Methyl Beta-Cyclodextrin (CAS 128446-36-6) is a cosmetic cosmetic ingredient functioning as Primary barrier. EU Regulation 1223/2009 status: permitted, max 0.18%. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 128446-36-6 →
Auto-generated CPSR Part A draft with source citations
Function
Primary barrier
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
EU Max Conc.
0.18%
US US Status
permitted
US Notes
CIR for this specific ingredient, as no dedicated safety assessment dossier has been published for Methyl Beta-Cyclodextrin in cosmetics.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Methyl Beta-Cyclodextrin.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
deodorant
{"cas_number": "51230-94-5", "ingredient_class": "odor_absorber", "mechanism_of_action": "odor_absorption", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "12-24", "odor_reduction_pct": "50-70", "bacteriostatic": "no", "bactericidal": "no", "microbiome_impact": "neutral", "axillary_microbiome_effect": "varies by ingredient", "MIC_value_if_antimicrobial": "varies", …
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Chelating agent
Expert Verdict
Expert safety assessment and concern-level summary for Methyl Beta-Cyclodextrin.
Known Synonyms
beta-Cyclodextrin, methyl ethers
O-Methyl-beta-cyclodextrin (1.8 methyls per saccharide)
Chemical Function
Chelating agent
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Methyl Beta-Cyclodextrin allowed in the EU?
Methyl Beta-Cyclodextrin EU regulatory status: permitted. Maximum allowed concentration: 0.18%. This is based on EU Regulation 1223/2009 and its amendments.
What does Methyl Beta-Cyclodextrin do in cosmetics?
Methyl Beta-Cyclodextrin functions as: Primary barrier. It is classified as a cosmetic ingredient in our database. CAS number: 128446-36-6.
Compliance Tools
Check Methyl Beta-Cyclodextrin compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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