Methyl Beta-Cyclodextrin

INCI: METHYL BETA-CYCLODEXTRIN

CAS Number
128446-36-6
Function
Primary barrier
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. 0.18%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR for this specific ingredient, as no dedicated safety assessment dossier has been published for Methyl Beta-Cyclodextrin in cosmetics.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Methyl Beta-Cyclodextrin is permitted in EU and US but lacks a dedicated safety assessment dossier; use within established regulatory limits.

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Concern Level: Moderate

Regulatory Flags

CMR

Frequently Asked Questions

Is Methyl Beta-Cyclodextrin safe in cosmetics?

Methyl Beta-Cyclodextrin is permitted in EU and US but lacks a dedicated safety assessment dossier; use within established regulatory limits. The EU classifies Methyl Beta-Cyclodextrin as "permitted". Safety rating: MODERATE.

Is Methyl Beta-Cyclodextrin allowed in the EU?

Methyl Beta-Cyclodextrin EU regulatory status: permitted. Maximum allowed concentration: 0.18%. This is based on EU Regulation 1223/2009 and its amendments.

What does Methyl Beta-Cyclodextrin do in cosmetics?

Methyl Beta-Cyclodextrin functions as: Primary barrier. It is classified as a Cosmetic Ingredient in our database. CAS number: 128446-36-6.

What is the Margin of Safety for Methyl Beta-Cyclodextrin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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