Morinda Citrifolia Fruit Extract

INCI: MORINDA CITRIFOLIA FRUIT EXTRACT

CAS Number
84929-68-0
Function
Skin conditioning, antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA-specific restriction on cosmetic use. Not classified as an OTC monographed active ingredient and has no GRAS/GRASE status for cosmetic application. No CIR final report or Safety Literature Review published. Falls under general botanical extract framework with no pre-market approval required.

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Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Morinda Citrifolia Fruit Extract is permitted in the EU with no Annex restrictions and allowed under EU Cosmetics Regulation 1223/2009. In the US, it falls under the general cosmetic ingredient framework with no FDA-specific restrictions. In vivo dermal toxicity studies in rats showed no treatment-related effects up to 5,000 mg/kg acute and 2,000 mg/kg/day subacute dosing. Key safety gaps include lack of HRIPT, dermal penetration data, phototoxicity data, and MoS; scopoletin and anthraquinone content warrant additional screening.

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Concern Level: Moderate

Regulatory Flags

no-cir-report no-sccs-opinion data-gap-dermal-absorption data-gap-hript data-gap-phototoxicity coumarin-content anthraquinone-monitor mos-not-calculable novel-food-authorized-eu-oral

Frequently Asked Questions

Is Morinda Citrifolia Fruit Extract safe in cosmetics?

Morinda Citrifolia Fruit Extract is permitted in the EU with no Annex restrictions and allowed under EU Cosmetics Regulation 1223/2009. In the US, it falls under the general cosmetic ingredient framework with no FDA-specific restrictions. In vivo dermal toxicity studies in rats showed no treatment-related effects up to 5,000 mg/kg acute and 2,000 mg/kg/day subacute dosing. Key safety gaps include lack of HRIPT, dermal penetration data, phototoxicity data, and MoS; scopoletin and anthraquinone content warrant additional screening. The EU classifies Morinda Citrifolia Fruit Extract as "permitted". Safety rating: MODERATE.

Is Morinda Citrifolia Fruit Extract allowed in the EU?

Morinda Citrifolia Fruit Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Morinda Citrifolia Fruit Extract do in cosmetics?

Morinda Citrifolia Fruit Extract functions as: Skin conditioning, antioxidant. It is classified as a Active Ingredient in our database. CAS number: 84929-68-0.

What is the Margin of Safety for Morinda Citrifolia Fruit Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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