Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
SCCS NOAEL Values
NOAEL/LOAEL values cited in official SCCS opinions for Nano Titanium Dioxide.
| NOAEL | LOAEL | Route | Species | Study | DA% (SCCS) | Opinion |
|---|---|---|---|---|---|---|
| - | - | Inhalation | Rat | Subchronic (90-day) (90 days (inhalation, 6h/day)) | N/A | SCCS/1617/20 (2020) |
Dermal Penetration Profile
Skin absorption and penetration characteristics of Nano Titanium Dioxide, relevant to systemic exposure and MoS calculations.
Source: SCCS/1516/13
Expert Verdict
Titanium Dioxide is prohibited in cosmetics in the EU due to safety concerns, though permitted as an OTC drug ingredient in the US.
Regulatory Flags
Frequently Asked Questions
Is Nano Titanium Dioxide safe in cosmetics?
Titanium Dioxide is prohibited in cosmetics in the EU due to safety concerns, though permitted as an OTC drug ingredient in the US. The EU classifies Nano Titanium Dioxide as "prohibited". Safety rating: MODERATE.
Is Nano Titanium Dioxide allowed in the EU?
Nano Titanium Dioxide EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Nano Titanium Dioxide do in cosmetics?
Nano Titanium Dioxide functions as: UV Filter. It is classified as a UV Filter / Sunscreen in our database. CAS number: None.
What is the Margin of Safety for Nano Titanium Dioxide?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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