Excellent Cosmetic Ingredient

Oat Beta-Glucan (Avena Sativa Kernel Extract)

INCI: AVENA SATIVA KERNEL EXTRACT

CAS Number

84012-26-0

Function

Beta-glucan (1,3/1,6-linked polysaccharide) from Avena sativa (oat) kernel providing deep hydration via CD44 receptor binding, immunomodulation, and collagen stimulation. Co-extracted avenanthramides provide anti-histamine and anti-inflammatory soothing activity. FDA-approved OTC skin protectant for dry skin and eczema.

Safety Rating

EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted

🇺🇸 US Status permitted

US Notes Colloidal oat (including oat beta-glucan-rich preparations) is FDA-approved as OTC skin protectant for dry skin and eczema relief at 0.003% minimum concentration. Cosmetic use unrestricted. MoCRA safety substantiation required.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)

adequate

Dermal Absorption

moderate

Sensitization

none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Oat beta-glucan combines proven barrier-support activity of beta-glucan polysaccharides with unique oat-specific avenanthramide soothing properties, making it preferred for sensitive-skin and eczema-adjacent formulations. FDA OTC skin protectant approval provides regulatory confidence. Outstanding safety profile with no contact sensitization from polysaccharide fraction.

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Concern Level: None

Regulatory Flags

barrier-function longevity-skincare soothing fda-otc-approved eczema-safe evidence-backed

Frequently Asked Questions

Is Oat Beta-Glucan (Avena Sativa Kernel Extract) safe in cosmetics?

Is Oat Beta-Glucan (Avena Sativa Kernel Extract) allowed in the EU?

Oat Beta-Glucan (Avena Sativa Kernel Extract) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Oat Beta-Glucan (Avena Sativa Kernel Extract) do in cosmetics?

Oat Beta-Glucan (Avena Sativa Kernel Extract) functions as: Beta-glucan (1,3/1,6-linked polysaccharide) from Avena sativa (oat) kernel providing deep hydration via CD44 receptor binding, immunomodulation, and collagen stimulation. Co-extracted avenanthramides provide anti-histamine and anti-inflammatory soothing activity. FDA-approved OTC skin protectant for dry skin and eczema.. It is classified as a Cosmetic Ingredient in our database. CAS number: 84012-26-0.

What is the Margin of Safety for Oat Beta-Glucan (Avena Sativa Kernel Extract)?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Oat Beta-Glucan (Avena Sativa Kernel Extract) compliance across multiple jurisdictions:

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Ingredient Decoder

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82 Allergen Checker

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Substance Compliance

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MoS Calculator

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Heavy Metal Limits

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