Good Cosmetic Ingredient NOAEL Data

PCA

CAS Number
98-79-3
Function
Humectant, Moisturising
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes CIR: SQ - IJT 18(S2):25-34, 1999

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

1 study endpoint found for PCA. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL >1000 mg/kg bw/day oral rat oral REACH

Expert Verdict

PCA is listed in the EU CosIng database with functions: Humectant, Moisturising It is permitted in the EU without specific restrictions.

โš ๏ธ
Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted humectant needs-enrichment

Frequently Asked Questions

Is PCA safe in cosmetics?

PCA is listed in the EU CosIng database with functions: Humectant, Moisturising It is permitted in the EU without specific restrictions. The EU classifies PCA as "Permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is PCA allowed in the EU?

PCA EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PCA do in cosmetics?

PCA functions as: Humectant, Moisturising. It is classified as a cosmetic ingredient in our database. CAS number: 98-79-3.

What is the NOAEL for PCA?

The NOAEL (No Observed Adverse Effect Level) for PCA is >1000 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

๐Ÿ“ฑ

Is PCA in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for PCA in your formulation.