Perfluorohexylethyl Triethoxysilane
INCI: PERFLUOROHEXYLETHYL TRIETHOXYSILANE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Perfluorohexylethyl Triethoxysilane. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 50 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Tier 1 high-risk PFAS flagged by FDA for safety concern; triethoxysilane group hydrolyzes to release ethanol and silanol; confirmed PFHxA precursor.
Frequently Asked Questions
Is Perfluorohexylethyl Triethoxysilane safe in cosmetics?
Tier 1 high-risk PFAS flagged by FDA for safety concern; triethoxysilane group hydrolyzes to release ethanol and silanol; confirmed PFHxA precursor. The EU classifies Perfluorohexylethyl Triethoxysilane as "prohibited". Safety rating: POOR. 1 toxicological study endpoint(s) are available in our database.
Is Perfluorohexylethyl Triethoxysilane allowed in the EU?
Perfluorohexylethyl Triethoxysilane EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Perfluorohexylethyl Triethoxysilane do in cosmetics?
Perfluorohexylethyl Triethoxysilane functions as: Binder, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 51851-37-7.
What is the Margin of Safety for Perfluorohexylethyl Triethoxysilane?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Perfluorohexylethyl Triethoxysilane?
The NOAEL (No Observed Adverse Effect Level) for Perfluorohexylethyl Triethoxysilane is 50 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
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Related Ingredients
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