Piper Methysticum Leaf/Root/Stem Extract
INCI: PIPER METHYSTICUM LEAF/ROOT/STEM EXTRACT
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
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Expert Verdict
CIR concluded insufficient data; hepatotoxicity from oral route well-documented; dermal absorption of kavain, methysticin, yangonin unresolved; use concentration 0.0001–0.1%; safety assessment likely to require supplemental dermal penetration and repeat-dose dermal toxicity studies
Regulatory Flags
Frequently Asked Questions
Is Piper Methysticum Leaf/Root/Stem Extract safe in cosmetics?
CIR concluded insufficient data; hepatotoxicity from oral route well-documented; dermal absorption of kavain, methysticin, yangonin unresolved; use concentration 0.0001–0.1%; safety assessment likely to require supplemental dermal penetration and repeat-dose dermal toxicity studies The EU classifies Piper Methysticum Leaf/Root/Stem Extract as "permitted". Safety rating: POOR.
Is Piper Methysticum Leaf/Root/Stem Extract allowed in the EU?
Piper Methysticum Leaf/Root/Stem Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Piper Methysticum Leaf/Root/Stem Extract do in cosmetics?
Piper Methysticum Leaf/Root/Stem Extract functions as: Skin Conditioning, Toning Agent. It is classified as a cosmetic ingredient in our database. CAS number: 84696-40-2.
What is the Margin of Safety for Piper Methysticum Leaf/Root/Stem Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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