Piper Methysticum Rhizome/Root Extract

INCI: PIPER METHYSTICUM RHIZOME/ROOT EXTRACT

CAS Number
84696-40-2 (shared with other kava extracts)
Function
Skin Conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Same FDA 2002 advisory as above; no cosmetic-specific ban

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Rhizome/root contains highest kavalactone concentration; flavokavains A and B in root show hepatotoxic and potentially pro-oxidant activity; requires full toxicological dossier before CPSR submission.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Piper Methysticum Rhizome/Root Extract safe in cosmetics?

Rhizome/root contains highest kavalactone concentration; flavokavains A and B in root show hepatotoxic and potentially pro-oxidant activity; requires full toxicological dossier before CPSR submission. The EU classifies Piper Methysticum Rhizome/Root Extract as "permitted". Safety rating: POOR.

Is Piper Methysticum Rhizome/Root Extract allowed in the EU?

Piper Methysticum Rhizome/Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Piper Methysticum Rhizome/Root Extract do in cosmetics?

Piper Methysticum Rhizome/Root Extract functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84696-40-2 (shared with other kava extracts).

What is the Margin of Safety for Piper Methysticum Rhizome/Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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