Placental Enzymes

INCI: PLACENTAL ENZYMES

CAS Number
Not specifically assigned
Function
Hair conditioning, skin conditioning, miscellaneous
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA permits animal-derived placental enzymes but warns against estrogenic and biologically active content. Products claiming placental extract may be deemed misbranded drugs.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

HIGH RISK. CIR Expert Panel found insufficient data for safety conclusion. Required data includes sensitization at use concentration, repeated-dose dermal toxicity, photosensitization, genotoxicity in mammalian systems, and proof of absence of hormonal and endocrine activity. Hepatotoxicity signals observed in animal studies. BSE/TSE prion transmission risk for bovine-derived material. Must be free of detectable pathogenic viruses and infectious agents.

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Placental Enzymes safe in cosmetics?

HIGH RISK. CIR Expert Panel found insufficient data for safety conclusion. Required data includes sensitization at use concentration, repeated-dose dermal toxicity, photosensitization, genotoxicity in mammalian systems, and proof of absence of hormonal and endocrine activity. Hepatotoxicity signals observed in animal studies. BSE/TSE prion transmission risk for bovine-derived material. Must be free of detectable pathogenic viruses and infectious agents. The EU classifies Placental Enzymes as "prohibited". Safety rating: POOR.

Is Placental Enzymes allowed in the EU?

Placental Enzymes EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Placental Enzymes do in cosmetics?

Placental Enzymes functions as: Hair conditioning, skin conditioning, miscellaneous. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned.

What is the Margin of Safety for Placental Enzymes?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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