Placental Extract

INCI: PLACENTAL EXTRACT

CAS Number
84195-59-5 (Placenta, ext.)
Function
Skin conditioning, biological additive (claimed)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes FDA considers products claiming placental extract potentially misbranded drugs; recommends renaming to describe composition accurately if hormones are removed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Potential estrogenic and endocrine activity with pathogenic virus and prion transmission risk; hepatotoxicity noted in animal studies; not recognized as formal INCI ingredient.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Placental Extract safe in cosmetics?

Potential estrogenic and endocrine activity with pathogenic virus and prion transmission risk; hepatotoxicity noted in animal studies; not recognized as formal INCI ingredient. The EU classifies Placental Extract as "prohibited". Safety rating: POOR.

Is Placental Extract allowed in the EU?

Placental Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Placental Extract do in cosmetics?

Placental Extract functions as: Skin conditioning, biological additive (claimed). It is classified as a cosmetic ingredient in our database. CAS number: 84195-59-5 (Placenta, ext.).

What is the Margin of Safety for Placental Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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