Placental Protein

INCI: PLACENTAL PROTEIN

CAS Number
84195-59-5
Function
Hair conditioning; skin conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Reported in FDA VCRP at approximately 0.2% concentration; must be free of metabolic and endocrine activity

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Placental proteins exhibit growth hormone-like anabolic effects; oral studies in rats showed testicular atrophy and hepatic lipidosis at dietary concentrations; sensitization, genotoxicity, and reproductive toxicity data are needed.

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Placental Protein safe in cosmetics?

Placental proteins exhibit growth hormone-like anabolic effects; oral studies in rats showed testicular atrophy and hepatic lipidosis at dietary concentrations; sensitization, genotoxicity, and reproductive toxicity data are needed. The EU classifies Placental Protein as "prohibited". Safety rating: POOR.

Is Placental Protein allowed in the EU?

Placental Protein EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Placental Protein do in cosmetics?

Placental Protein functions as: Hair conditioning; skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84195-59-5.

What is the Margin of Safety for Placental Protein?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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