Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Polysilicone-15. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| LOAEL | 60 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Dermal Penetration Profile
Skin absorption and penetration characteristics of Polysilicone-15, relevant to systemic exposure and MoS calculations.
Source: SCCS Opinion
Expert Verdict
Good safety profile with negligible skin penetration; generally considered safe for cosmetic use.
Regulatory Flags
Frequently Asked Questions
Is Polysilicone-15 safe in cosmetics?
Good safety profile with negligible skin penetration; generally considered safe for cosmetic use. The EU classifies Polysilicone-15 as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.
Is Polysilicone-15 allowed in the EU?
Polysilicone-15 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Polysilicone-15 do in cosmetics?
Polysilicone-15 functions as: UVB filter (280-320 nm, peak 312 nm). It is classified as a UV Filter / Sunscreen in our database. CAS number: 207574-74-1.
What is the Margin of Safety for Polysilicone-15?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Polysilicone-15?
The NOAEL (No Observed Adverse Effect Level) for Polysilicone-15 is 60 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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