Procapil

INCI: PROCAPIL

CAS Number
None
Function
hair-growth active; follicle anchor strengthener; DHT inhibitor; anti-inflammatory; anagen:telogen ratio improver
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. 3%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted cosmetic active at 3% suggested use level. Appearance-based claims required to avoid drug classification.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Procapil is a proprietary complex of Biotinyl-GHK, Apigenin, and Oleanolic acid targeting dermal papilla cells. Biotinyl-GHK strengthens follicle anchoring; Apigenin inhibits DHT and reduces perifollicular inflammation; Oleanolic acid improves scalp microcirculation. Clinical studies demonstrate significant improvement in anagen:telogen ratio, hair density, and thickness with no adverse effects reported. Recommended use level: 3%.

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Concern Level: Low

Regulatory Flags

proprietary-complex hair-growth-active dht-inhibitor cosmetic-classified rcp-study-evidenced fphl-clinical-data dermal-papilla-targeted

Frequently Asked Questions

Is Procapil safe in cosmetics?

Procapil is a proprietary complex of Biotinyl-GHK, Apigenin, and Oleanolic acid targeting dermal papilla cells. Biotinyl-GHK strengthens follicle anchoring; Apigenin inhibits DHT and reduces perifollicular inflammation; Oleanolic acid improves scalp microcirculation. Clinical studies demonstrate significant improvement in anagen:telogen ratio, hair density, and thickness with no adverse effects reported. Recommended use level: 3%. The EU classifies Procapil as "permitted". Safety rating: GOOD.

Is Procapil allowed in the EU?

Procapil EU regulatory status: permitted. Maximum allowed concentration: 3%. This is based on EU Regulation 1223/2009 and its amendments.

What does Procapil do in cosmetics?

Procapil functions as: hair-growth active; follicle anchor strengthener; DHT inhibitor; anti-inflammatory; anagen:telogen ratio improver. It is classified as a Active Ingredient in our database. CAS number: None.

What is the Margin of Safety for Procapil?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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