Is Pycnogenol (Pinus Pinaster Bark Extract) safe in cosmetics?
Pycnogenol (Pinus Pinaster Bark Extract) has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Pycnogenol (Pinus Pinaster Bark Extract)
Also known as: EINECS 290-166-2
INCI: PYCNOGENOL
Pycnogenol (Pinus Pinaster Bark Extract) (CAS 90082-75-0) is a cosmetic fragrance functioning as Antioxidant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 90082-75-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Pycnogenol (Pinus Pinaster Bark Extract) is classified GHS Danger (H226, H304, H315, H317, H400, H410) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Antioxidant
Safety Rating
GOOD
Chemistry & Identifiers
EC Number
290-166-2
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Recognized only titanium dioxide and zinc oxide as permitted mineral sunscreens.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Pycnogenol (Pinus Pinaster Bark Extract).
Calculate MoS for your specific formulation with the MoS Calculator.
Dermal Penetration Profile
Skin absorption and penetration characteristics of Pycnogenol (Pinus Pinaster Bark Extract), relevant to systemic exposure and MoS calculations.
Absorption %
6-12%
Penetration Level
epidermis
Penetration Depth
epidermis
Molecular Weight
Variable Da
Log P
n/a
Systemic Absorption
minimal
Topical Bioavailability
4-10%
Safety Margin Factor
moderate
Vehicle Dependent
Yes — absorption varies by formulation
Source: Clin Cosmet Investig Dermatol 2012
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (III - Restricted)
BRIN Brazil/India Cosmetics
India: Restricted
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Additional Ingredient Properties
6 property records from structured ingredient metadata.
acne
{"cas_number": "133248-87-0", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-10", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restricti…
dermal_absorption
{"molecular_weight_da": "Variable", "skin_penetration_level": "epidermis", "penetration_depth": "epidermis", "absorption_pct": "6-12", "systemic_absorption": "minimal", "penetration_enhancer": "no", "occlusion_effect": "no", "vehicle_dependent": "yes", "skin_barrier_effect": "strengthens", "bioavailability_topical_pct": "4-10", "safety_margin_factor": "moderate", "source": "Clin Cosmet Investig De…
self_tanning
{"cas_number": "133248-87-0", "ingredient_class": "tan_extender", "tanning_mechanism": "other", "color_development_onset_hours": "0.0", "full_color_development_hours": "0", "color_duration_days": "0", "DHA_concentration_if_applicable_pct": "0", "erythrulose_concentration_pct": "0", "pH_dependent_color": "no", "formaldehyde_release_concern": "no", "formaldehyde_release_ppm": "0", "AGE_formation_con…
skin_suitability
{"oily_skin": "acceptable", "dry_skin": "acceptable", "sensitive_skin": "recommended", "combination_skin": "acceptable", "normal_skin": "acceptable", "acne_prone": "acceptable", "rosacea": "recommended", "eczema": "acceptable", "hyperpigmentation": "acceptable", "aging_mature": "recommended", "dehydrated": "acceptable", "skin_benefit_primary": "antioxidant", "skin_benefit_secondary": "anti-inflamm…
synergy
{"inci_name_2": "Vitamin C + Coenzyme Q10", "synergy_type": "antioxidant-synergy", "synergy_description": "Pine bark extract enhances vitamin stability and activity", "combined_benefit": "Prolonged vitamin C activity, enhanced mitochondrial protection, superior antioxidant power", "efficacy_multiplier": "2.8x", "mechanism_of_action": "Pycnogenol proanthocyanidins regenerate vitamin C; CoQ10 adds m…
uv_stability
{"uv_stable": "partially", "uv_degradation_rate": "moderate", "photosensitizer": "no", "phototoxic": "no", "photoallergic": "no", "requires_uv_protection_packaging": "no", "color_change_uv": "no", "odor_change_uv": "no", "efficacy_loss_uv_pct": "20", "spf_contribution": "no", "uva_protection": "no", "uvb_protection": "no", "photostable_sunscreen": "no", "boost_spf_of_others": "no", "antioxidant_un…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-dandruff
Antioxidant
Biocide
Fragrance
Softener and conditioner
UV stabilizer
Regulatory List Membership (1)
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Pycnogenol (Pinus Pinaster Bark Extract).
Regulatory Flags
eu_cosing_listed
Known Synonyms
EINECS 290-166-2
Chemical Function
Biocide
UV stabilizer
Antioxidant
Softener and conditioner
Fragrance
Anti-dandruff
Regulatory Lists
Europe
Personal care
restricted
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Pycnogenol (Pinus Pinaster Bark Extract) allowed in the EU?
Pycnogenol (Pinus Pinaster Bark Extract) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Pycnogenol (Pinus Pinaster Bark Extract) do in cosmetics?
Pycnogenol (Pinus Pinaster Bark Extract) functions as: Antioxidant. It is classified as a Fragrance in our database. CAS number: 90082-75-0.
Is Pycnogenol (Pinus Pinaster Bark Extract) used outside cosmetics?
Pycnogenol (Pinus Pinaster Bark Extract) also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Pycnogenol (Pinus Pinaster Bark Extract) have different safety status in cosmetics vs industrial chemicals?
Pycnogenol (Pinus Pinaster Bark Extract) is classified GHS Danger (H226, H304, H315, H317, H400, H410) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Pycnogenol (Pinus Pinaster Bark Extract) compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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