Regulatory Status
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Safety Data
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Expert Verdict
🚫 EU-banned. NTP 2-yr dermal study: equivocal evidence of carcinogenicity in male mice (squamous cell papilloma), some evidence in female mice (squamous cell carcinoma). Mutagenic in Ames test (TA100). In vitro corrosive to reconstructed human epidermis. Hepatotoxic in animal studies. Confirmed skin sensitizer. Do NOT formulate. [^1_8][^1_9]
Regulatory Flags
Frequently Asked Questions
Is Pyrogallol safe in cosmetics?
🚫 EU-banned. NTP 2-yr dermal study: equivocal evidence of carcinogenicity in male mice (squamous cell papilloma), some evidence in female mice (squamous cell carcinoma). Mutagenic in Ames test (TA100). In vitro corrosive to reconstructed human epidermis. Hepatotoxic in animal studies. Confirmed skin sensitizer. Do NOT formulate. [^1_8][^1_9] The EU classifies Pyrogallol as "prohibited". Safety rating: POOR.
Is Pyrogallol allowed in the EU?
Pyrogallol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Pyrogallol do in cosmetics?
Pyrogallol functions as: Hair Dyeing agent (historical); Antioxidant / Reducing agent [^1_8]. It is classified as a cosmetic ingredient in our database. CAS number: 87-66-1 [^1_8][^1_3].
What is the Margin of Safety for Pyrogallol?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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