Good Colorant NOAEL Data

Red 28 Lake (CI 45410)__

INCI: RED 28 LAKE (CI 45410)

CAS Number
18472-87-2
Function
Colorant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. 0.4%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Red 28 Lake (CI 45410)__. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
LOAEL 10 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

Red 28 Lake (CI 45410) is generally considered safe for use as a cosmetic colorant.

โš ๏ธ
Concern Level: Low

Regulatory Flags

eu_children_restricted eu_cosing_listed

Frequently Asked Questions

Is Red 28 Lake (CI 45410)__ safe in cosmetics?

Red 28 Lake (CI 45410) is generally considered safe for use as a cosmetic colorant. The EU classifies Red 28 Lake (CI 45410)__ as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is Red 28 Lake (CI 45410)__ allowed in the EU?

Red 28 Lake (CI 45410)__ EU regulatory status: permitted. Maximum allowed concentration: 0.4%. This is based on EU Regulation 1223/2009 and its amendments.

What does Red 28 Lake (CI 45410)__ do in cosmetics?

Red 28 Lake (CI 45410)__ functions as: Colorant. It is classified as a Colorant in our database. CAS number: 18472-87-2.

What is the Margin of Safety for Red 28 Lake (CI 45410)__?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Red 28 Lake (CI 45410)__?

The NOAEL (No Observed Adverse Effect Level) for Red 28 Lake (CI 45410)__ is 10 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.

๐Ÿ“ฑ

Is Red 28 Lake (CI 45410)__ in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Red 28 Lake (CI 45410)__ in your formulation.