Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
9 study endpoints found for Sodium Acetate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 102 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 21 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
| dose_tested | 102 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | >=57.44 other | oral | - | oral | REACH |
| NOAEL | >=0.05 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=3600 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=21 other | oral | rat | oral | REACH |
| NOAEL | >=0.01 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=50 mg/kg bw/day | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Sodium acetate is restricted under EU regulations but permitted in the US, with CIR concluding it is safe at current use levels and concentrations in cosmetics.
Regulatory Flags
Frequently Asked Questions
Is Sodium Acetate safe in cosmetics?
Sodium acetate is restricted under EU regulations but permitted in the US, with CIR concluding it is safe at current use levels and concentrations in cosmetics. The EU classifies Sodium Acetate as "restricted". Safety rating: GOOD. 9 toxicological study endpoint(s) are available in our database.
Is Sodium Acetate allowed in the EU?
Sodium Acetate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Acetate do in cosmetics?
Sodium Acetate functions as: Insufficient data. It is classified as a Cosmetic Ingredient in our database. CAS number: 127-09-3.
What is the Margin of Safety for Sodium Acetate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sodium Acetate?
The NOAEL (No Observed Adverse Effect Level) for Sodium Acetate is 102 mg/kg bw/day based on a Chronic study via oral route in rat. A total of 9 study endpoints are available. Source: COSMOS_DB.
Is Sodium Acetate classified as hazardous under GHS?
Sodium Acetate carries a GHS signal word of "WARNING". Hazard statements: Causes eye irritation. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.
Compliance Tools
Check Sodium Acetate compliance across multiple jurisdictions:
Related Ingredients
Is Sodium Acetate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Sodium Acetate in your formulation.