Toluene-3,4-Diamine

INCI: TOLUENE-3,4-DIAMINE

CAS Number
496-72-0
Function
Hair dye intermediate (historically used)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not approved for cosmetic use; not included in FDA positive lists

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

๐Ÿšซ Prohibited in EU cosmetics (Annex II); part of the "toluidines and their isomers" prohibition group; suspected mutagen; not to be used in any cosmetic formulation

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Concern Level: High

Regulatory Flags

eu_banned_cosmetics eu_cosing_listed

Frequently Asked Questions

Is Toluene-3,4-Diamine safe in cosmetics?

๐Ÿšซ Prohibited in EU cosmetics (Annex II); part of the "toluidines and their isomers" prohibition group; suspected mutagen; not to be used in any cosmetic formulation The EU classifies Toluene-3,4-Diamine as "prohibited". Safety rating: POOR.

Is Toluene-3,4-Diamine allowed in the EU?

Toluene-3,4-Diamine EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Toluene-3,4-Diamine do in cosmetics?

Toluene-3,4-Diamine functions as: Hair dye intermediate (historically used). It is classified as a cosmetic ingredient in our database. CAS number: 496-72-0.

What is the Margin of Safety for Toluene-3,4-Diamine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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