Regulatory Status
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Safety Data
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Expert Verdict
🚨 CRITICAL: Known teratogen; causes birth defects (cleft lip/palate); CNS depressant; metabolic acidosis risk; California Prop 65 warning; pharmaceutical-grade ingredient with no legitimate cosmetic application; do NOT formulate with this ingredient
Regulatory Flags
Frequently Asked Questions
Is Topiramate safe in cosmetics?
🚨 CRITICAL: Known teratogen; causes birth defects (cleft lip/palate); CNS depressant; metabolic acidosis risk; California Prop 65 warning; pharmaceutical-grade ingredient with no legitimate cosmetic application; do NOT formulate with this ingredient The EU classifies Topiramate as "permitted". Safety rating: POOR.
Is Topiramate allowed in the EU?
Topiramate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Topiramate do in cosmetics?
Topiramate functions as: Skin conditioning (CosIng listing), though primarily known as an anticonvulsant/pharmaceutical active. It is classified as a cosmetic ingredient in our database. CAS number: 97240-79-4.
What is the Margin of Safety for Topiramate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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