Transforming Growth Factor Beta (TGF-β)

INCI: TRANSFORMING GROWTH FACTOR BETA

CAS Number
None
Function
skin-conditioning and anti-aging active
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status restricted
US Notes CIR (Cosmetic Ingredient Review) safety assessment has been published for TGF-β specifically. Regulated as OTC drug in certain applications.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Insufficient safety data available for TGF-β; further assessment and CIR review recommended before use in cosmetic formulations.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Transforming Growth Factor Beta (TGF-β) safe in cosmetics?

Insufficient safety data available for TGF-β; further assessment and CIR review recommended before use in cosmetic formulations. The EU classifies Transforming Growth Factor Beta (TGF-β) as "permitted". Safety rating: MODERATE.

Is Transforming Growth Factor Beta (TGF-β) allowed in the EU?

Transforming Growth Factor Beta (TGF-β) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Transforming Growth Factor Beta (TGF-β) do in cosmetics?

Transforming Growth Factor Beta (TGF-β) functions as: skin-conditioning and anti-aging active. It is classified as a Active Ingredient in our database. CAS number: None.

What is the Margin of Safety for Transforming Growth Factor Beta (TGF-β)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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