Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Tricalcium Phosphate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 6.67 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 6.67 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
Standard mineral QC applies (heavy metals per usual batch testing); commonly used as talc replacement
Regulatory Flags
Frequently Asked Questions
Is Tricalcium Phosphate safe in cosmetics?
Standard mineral QC applies (heavy metals per usual batch testing); commonly used as talc replacement The EU classifies Tricalcium Phosphate as "permitted". Safety rating: EXCELLENT. 2 toxicological study endpoint(s) are available in our database.
Is Tricalcium Phosphate allowed in the EU?
Tricalcium Phosphate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tricalcium Phosphate do in cosmetics?
Tricalcium Phosphate functions as: Opacifier, abrasive, anti-caking agent, oral care/remineralization agent, bulking agent. It is classified as a cosmetic ingredient in our database. CAS number: 7758-87-4.
What is the Margin of Safety for Tricalcium Phosphate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Tricalcium Phosphate?
The NOAEL (No Observed Adverse Effect Level) for Tricalcium Phosphate is 6.67 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
Check Tricalcium Phosphate compliance across multiple jurisdictions:
Related Ingredients
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