Good UV Filter / Sunscreen NOAEL Data

Tris-Biphenyl Triazine (Tinosorb A2B)

INCI: TRIS-BIPHENYL TRIAZINE

Tris-Biphenyl Triazine (Tinosorb A2B) (CAS 31274-51-8) is a cosmetic uv filter / sunscreen functioning as UV Absorber / UV Filter (broad-spectrum). NOAEL 1000 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted, max 10%. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 31274-51-8 →

Auto-generated CPSR Part A draft with source citations
Function
UV Absorber / UV Filter (broad-spectrum)
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C39H27N3
MW
537.6 g/mol
EC Number
479-950-7
PubChem CID
11628027
IUPAC Name
2,4,6-tris(4-phenylphenyl)-1,3,5-triazine
InChIKey
CENPSTJGQOQKKW-UHFFFAOYSA-N

Regulatory Status

EU EU Status restricted
EU Max Conc. 10%
US US Status permitted
US Notes No specific restrictions

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Tris-Biphenyl Triazine (Tinosorb A2B).

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Tris-Biphenyl Triazine (Tinosorb A2B). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =1000 mg/kg bw/day oral Rat developmental ToxValDB_ECHA_IUCLID

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for Tris-Biphenyl Triazine (Tinosorb A2B) across SCCS product categories, with measured dermal absorption where available.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

EU CosIng Annex Listing

European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.

Annex VI — Permitted UV Filters
Max: 10%

Expanded Jurisdictional Detail

Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.

SA Saudi SFDA (VI - UV Filters)
Max: 0.1.
JPKR Japan/Korea Cosmetics
Korea (Restricted): max 10.0
BRIN Brazil/India Cosmetics
India: Permitted UV Filter · max 0.1
Additional Jurisdictional Restrictions (2)
Jurisdiction Status Max % Product Type
CN permitted_uv_filter 10 All cosmetics (no spray)
BR permitted_uv_filter 10 Sunscreen products; nanoform: primary particle >80nm, purity ≥98%, uncoated

Additional Ingredient Properties

3 property records from structured ingredient metadata.

anti_pollution
{"cas_number": "131-57-7", "ingredient_class": "blue_light_filter", "primary_mechanism": "film_forming_barrier", "pollution_types_targeted": "blue_light_HEV/UV_A", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation…
sunscreen_uv
{"cas_number": "31274-51-8", "uv_filter_type": "organic_broad_spectrum", "chemical_class": "triazine", "absorption_spectrum_nm_range": "290-380", "peak_absorption_wavelength_nm": "325", "molar_extinction_coefficient": "58000", "critical_wavelength_nm": "370", "UVA_PF": "14-22", "SPF_contribution_per_percent": "9.8", "photostability_rating": "photostable", "photodegradation_half_life_hours": ">24",…
uv_stability
{"uv_stable": "yes", "uv_degradation_rate": "stable", "photosensitizer": "no", "phototoxic": "no", "photoallergic": "no", "requires_uv_protection_packaging": "no", "color_change_uv": "no", "odor_change_uv": "no", "efficacy_loss_uv_pct": "0", "spf_contribution": "yes", "uva_protection": "yes", "uvb_protection": "yes", "photostable_sunscreen": "yes", "boost_spf_of_others": "no", "antioxidant_under_u…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
UV stabilizer
Regulatory List Membership (2)
EU Regulated in Personal Care EU CosIng Cosmetics Ingredient Database

Expert Verdict

Expert safety assessment and concern-level summary for Tris-Biphenyl Triazine (Tinosorb A2B).

Regulatory Flags

EU Restricted eu_cosing_listed

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Tris-Biphenyl Triazine (Tinosorb A2B) by CAS number or substance name.

Studies
1
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Chemical Function

UV stabilizer

Regulatory Lists

Europe; Personal care

Australian Status

AICIS status: listed_with_terms

Specific information requirements: Obligations to provide information apply. These obligations are: 1. A person introducing this chemical must tell us in writing within 28 calendar days if any of the following circumstances have occurred in relation to their introduction (importation or manufacture): a. the concentration of the chemical exceeds or is...

Frequently Asked Questions

Is Tris-Biphenyl Triazine (Tinosorb A2B) safe in cosmetics?

Tris-Biphenyl Triazine (Tinosorb A2B) has a safety rating of "GOOD" in our database. EU status: restricted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.

Is Tris-Biphenyl Triazine (Tinosorb A2B) allowed in the EU?

Tris-Biphenyl Triazine (Tinosorb A2B) EU regulatory status: restricted. Maximum allowed concentration: 10%. This is based on EU Regulation 1223/2009 and its amendments.

What does Tris-Biphenyl Triazine (Tinosorb A2B) do in cosmetics?

Tris-Biphenyl Triazine (Tinosorb A2B) functions as: UV Absorber / UV Filter (broad-spectrum). It is classified as a UV Filter / Sunscreen in our database. CAS number: 31274-51-8.

What is the NOAEL for Tris-Biphenyl Triazine (Tinosorb A2B)?

The NOAEL (No Observed Adverse Effect Level) for Tris-Biphenyl Triazine (Tinosorb A2B) is =1000 mg/kg bw/day based on a developmental study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.

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(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good Similar safety
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Tris-Biphenyl Triazine
Excellent Chemical family
UV Filter – most efficient UVB + UVA2...
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Good Browse nearby
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Perfuming

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