Poor Cosmetic Ingredient GHS Classified

Vinylidene Difluoride

INCI: VINYLIDENE DIFLUORIDE (1,1-DIFLUOROETHYLENE)

CAS Number
75-38-7
Function
Monomer/precursor for PVDF polymers; limited direct cosmetic use — primarily an industrial chemical
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not FDA-approved for direct cosmetic use; NIOSH REL: TWA 1 ppm

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
Rapid evaporation of the liquid may cause frostbite. The substance may cause effects on the central nervous system.
Routes of Exposure
The substance can be absorbed into the body by inhalation.

Expert Verdict

Major flags: extremely flammable gas; CNS toxicity (dizziness, headache, nausea); PFAS-related regulatory scrutiny; not suitable as cosmetic ingredient in monomer form; only acceptable as fully polymerized PVDF in specific applications

⚠️
Concern Level: High

Frequently Asked Questions

Is Vinylidene Difluoride safe in cosmetics?

Major flags: extremely flammable gas; CNS toxicity (dizziness, headache, nausea); PFAS-related regulatory scrutiny; not suitable as cosmetic ingredient in monomer form; only acceptable as fully polymerized PVDF in specific applications The EU classifies Vinylidene Difluoride as "permitted". Safety rating: POOR.

Is Vinylidene Difluoride allowed in the EU?

Vinylidene Difluoride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Vinylidene Difluoride do in cosmetics?

Vinylidene Difluoride functions as: Monomer/precursor for PVDF polymers; limited direct cosmetic use — primarily an industrial chemical. It is classified as a cosmetic ingredient in our database. CAS number: 75-38-7.

What is the Margin of Safety for Vinylidene Difluoride?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Vinylidene Difluoride compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

Anacardium Occidentale Peduncle Fiber
Moderate
Acrylic Acid/Stearyl Methacrylate/Dimethicone Methacrylate Copolymer
Moderate
Bis-HEA IPDI/PPG-53 Copolymer
Good
Acetyl Hexapeptide-8 Amide (Argireline)
Moderate
Hexamethylenediamine/MDI Copolymer
Good
Browse all 30,000+ ingredients →
📱

Is Vinylidene Difluoride in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Vinylidene Difluoride in your formulation.

Ingredient Decoder MoS Calculator