Excellent Antioxidant

VITIS VINIFERA SEED EXTRACT

CAS Number
84929-27-1
Function
Antioxidant; proanthocyanidin OPC complex; HAT/SET free radical scavenger; collagen cross-linker; MMP inhibitor; anti-inflammatory
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA restrictions. Classified as cosmetic botanical extract. Safe as used at typical cosmetic concentrations.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Dual anti-aging benefit: potent HAT/SET antioxidant with direct structural effect via collagen cross-linking and MMP inhibition. Typical use 0.5โ€“2%. In vitro antioxidant capacity does not directly predict in vivo efficacy; clinical substantiation expected by regulators. No regulatory restrictions.

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Concern Level: None

Regulatory Flags

antioxidant polyphenol opc proanthocyanidin botanical grape-seed hat-set-mechanism mmp-inhibitor collagen-cross-linking anti-aging natural-positioning

Frequently Asked Questions

Is VITIS VINIFERA SEED EXTRACT safe in cosmetics?

Dual anti-aging benefit: potent HAT/SET antioxidant with direct structural effect via collagen cross-linking and MMP inhibition. Typical use 0.5โ€“2%. In vitro antioxidant capacity does not directly predict in vivo efficacy; clinical substantiation expected by regulators. No regulatory restrictions. The EU classifies VITIS VINIFERA SEED EXTRACT as "permitted". Safety rating: EXCELLENT.

Is VITIS VINIFERA SEED EXTRACT allowed in the EU?

VITIS VINIFERA SEED EXTRACT EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does VITIS VINIFERA SEED EXTRACT do in cosmetics?

VITIS VINIFERA SEED EXTRACT functions as: Antioxidant; proanthocyanidin OPC complex; HAT/SET free radical scavenger; collagen cross-linker; MMP inhibitor; anti-inflammatory. It is classified as a Antioxidant in our database. CAS number: 84929-27-1.

What is the Margin of Safety for VITIS VINIFERA SEED EXTRACT?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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