Xylene

INCI: XYLENE

CAS Number
1330-20-7 (mixed isomers)
Function
Solvent
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not listed as a permitted cosmetic ingredient; classified as industrial solvent; FDA considers it unsafe for cosmetic application

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

BANNED in EU cosmetics; CNS depressant; reproductive/developmental toxicant; classified as harmful by inhalation and skin contact; EUH066 warning for repeated exposure

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Concern Level: High

Frequently Asked Questions

Is Xylene safe in cosmetics?

BANNED in EU cosmetics; CNS depressant; reproductive/developmental toxicant; classified as harmful by inhalation and skin contact; EUH066 warning for repeated exposure The EU classifies Xylene as "prohibited". Safety rating: POOR.

Is Xylene allowed in the EU?

Xylene EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Xylene do in cosmetics?

Xylene functions as: Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 1330-20-7 (mixed isomers).

What is the Margin of Safety for Xylene?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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