Yohimbe Bark Extract

INCI: PAUSINYSTALIA YOHIMBE BARK EXTRACT

CAS Number
85117-22-2
Function
Historically claimed as skin conditioning, lipolytic agent
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically listed on FDA's prohibited list, but yohimbine is a pharmacologically active alkaloid (ฮฑ2-adrenergic antagonist). Any cosmetic containing it must still meet general safety standards; use in cosmetics is highly problematic

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

EU-banned (Annex II). Cardiovascular effects including hypertension, tachycardia, CNS stimulation, and anxiety at pharmacological doses. Not suitable for cosmetic use in any jurisdiction adhering to EU-harmonized standards

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Yohimbe Bark Extract safe in cosmetics?

EU-banned (Annex II). Cardiovascular effects including hypertension, tachycardia, CNS stimulation, and anxiety at pharmacological doses. Not suitable for cosmetic use in any jurisdiction adhering to EU-harmonized standards The EU classifies Yohimbe Bark Extract as "prohibited". Safety rating: POOR.

Is Yohimbe Bark Extract allowed in the EU?

Yohimbe Bark Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Yohimbe Bark Extract do in cosmetics?

Yohimbe Bark Extract functions as: Historically claimed as skin conditioning, lipolytic agent. It is classified as a cosmetic ingredient in our database. CAS number: 85117-22-2.

What is the Margin of Safety for Yohimbe Bark Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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