Poor Cosmetic Ingredient SCCS/CIR Reviewed

2-Chloro-P-Phenylenediamine

INCI: 2-CHLORO-P-PHENYLENEDIAMINE

CAS Number
615-66-7
Function
Hair dyeing (oxidative dye intermediate)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA ban; coal-tar dye exemption with caution labeling

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir
Verdict: unknown

Expert Verdict

Genotoxic potential; banned in EU including all salts; SCCS recommended handling with same caution as genotoxic substances

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Concern Level: High

Regulatory Flags

eu_banned_cosmetics eu_cosing_listed

Frequently Asked Questions

Is 2-Chloro-P-Phenylenediamine safe in cosmetics?

Genotoxic potential; banned in EU including all salts; SCCS recommended handling with same caution as genotoxic substances The EU classifies 2-Chloro-P-Phenylenediamine as "prohibited". Safety rating: POOR. This ingredient has been reviewed by cir.

Is 2-Chloro-P-Phenylenediamine allowed in the EU?

2-Chloro-P-Phenylenediamine EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does 2-Chloro-P-Phenylenediamine do in cosmetics?

2-Chloro-P-Phenylenediamine functions as: Hair dyeing (oxidative dye intermediate). It is classified as a cosmetic ingredient in our database. CAS number: 615-66-7.

What is the Margin of Safety for 2-Chloro-P-Phenylenediamine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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