4,4'-Diaminodiphenylamine Sulfate

INCI: 4,4'-DIAMINODIPHENYLAMINE SULFATE

CAS Number
16523-31-2
Function
Hair Dye (oxidative)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Same as parent compound โ€” coal tar hair dye exemption with labeling requirements

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Prohibited in EU as aromatic amine hair dye; permitted in US under coal tar exemption with labeling requirements. Sulfate salt does not mitigate the aromatic amine hazard profile.

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Concern Level: High

Frequently Asked Questions

Is 4,4'-Diaminodiphenylamine Sulfate safe in cosmetics?

Prohibited in EU as aromatic amine hair dye; permitted in US under coal tar exemption with labeling requirements. Sulfate salt does not mitigate the aromatic amine hazard profile. The EU classifies 4,4'-Diaminodiphenylamine Sulfate as "prohibited". Safety rating: POOR.

Is 4,4'-Diaminodiphenylamine Sulfate allowed in the EU?

4,4'-Diaminodiphenylamine Sulfate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does 4,4'-Diaminodiphenylamine Sulfate do in cosmetics?

4,4'-Diaminodiphenylamine Sulfate functions as: Hair Dye (oxidative). It is classified as a cosmetic ingredient in our database. CAS number: 16523-31-2.

What is the Margin of Safety for 4,4'-Diaminodiphenylamine Sulfate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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