Is Acetyl Tetrapeptide-9 safe in cosmetics?
Acetyl Tetrapeptide-9 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Active Ingredient
Acetyl Tetrapeptide-9
Also known as: UNII-VMO8OOD3V0, L-Histidine, N2-acetyl-L-glutaminyl-L-alpha-Aspartyl-L-valyl-, N-Acetyl-gln-asp-val-his, Dermican
INCI: ACETYL TETRAPEPTIDE-9
Acetyl Tetrapeptide-9 (CAS 928006-50-2) is a cosmetic active ingredient functioning as Peptide anti-aging active. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 928006-50-2 →
Auto-generated CPSR Part A draft with source citations
Function
Peptide anti-aging active
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR report, no published NOAEL/MoS. The safety case relies on existing data.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Acetyl Tetrapeptide-9.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
anti_aging
{"anti_aging_claim": "firming, collagen-boosting", "mechanism_of_action": "Signal peptide for fibroblast activation", "target_skin_layer": "dermis", "collagen_stimulation": "Yes", "elastin_protection": "Moderate", "wrinkle_reduction_pct": "15-25", "clinical_study_duration_weeks": "8", "sample_size": "25", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journal": "JOCD, Int J Pept Re…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Acetyl Tetrapeptide-9.
Known Synonyms
UNII-VMO8OOD3V0
L-Histidine, N2-acetyl-L-glutaminyl-L-alpha-Aspartyl-L-valyl-
N-Acetyl-gln-asp-val-his
Dermican
Chemical Function
Softener and conditioner
Frequently Asked Questions
Is Acetyl Tetrapeptide-9 allowed in the EU?
Acetyl Tetrapeptide-9 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetyl Tetrapeptide-9 do in cosmetics?
Acetyl Tetrapeptide-9 functions as: Peptide anti-aging active. It is classified as a Active Ingredient in our database. CAS number: 928006-50-2.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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