Good UV Filter / Sunscreen NOAEL Data

Butyl Methoxydibenzoylmethane

INCI: BUTYL METHOXYDIBENZOYLMETHANE

CAS Number
70356-09-1
Function
UVA filter; sunscreen active; photostabilizer-dependent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. 5%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes OTC sunscreen drug active; max 4% per FDA; primary UVA filter in US sunscreens; photostabilization with octocrylene or ethylhexyl methoxycrylene required for photostability; marketed as Parsol 1789

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Butyl Methoxydibenzoylmethane. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 450 mg/kg bw/day oral rat oral REACH
NOAEL 360 mg/kg bw/day dermal code:3484 dermal REACH

Expert Verdict

Primary UVA filter in US sunscreens (max 4%) and EU (max 5%). Avobenzone requires mandatory photostabilization with octocrylene or ethylhexyl methoxycrylene to prevent photodegradation and associated sensitization risk. Photostabilized formulations are standard for broad-spectrum OTC sunscreens.

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Concern Level: Moderate

Regulatory Flags

sunscreen uva-filter photounstable requires-stabilizer otc-drug-us photoallergy men-s-sports ifra_fragrance eu_cosing_listed

Frequently Asked Questions

Is Butyl Methoxydibenzoylmethane safe in cosmetics?

Primary UVA filter in US sunscreens (max 4%) and EU (max 5%). Avobenzone requires mandatory photostabilization with octocrylene or ethylhexyl methoxycrylene to prevent photodegradation and associated sensitization risk. Photostabilized formulations are standard for broad-spectrum OTC sunscreens. The EU classifies Butyl Methoxydibenzoylmethane as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is Butyl Methoxydibenzoylmethane allowed in the EU?

Butyl Methoxydibenzoylmethane EU regulatory status: permitted. Maximum allowed concentration: 5%. This is based on EU Regulation 1223/2009 and its amendments.

What does Butyl Methoxydibenzoylmethane do in cosmetics?

Butyl Methoxydibenzoylmethane functions as: UVA filter; sunscreen active; photostabilizer-dependent. It is classified as a UV Filter / Sunscreen in our database. CAS number: 70356-09-1.

What is the Margin of Safety for Butyl Methoxydibenzoylmethane?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Butyl Methoxydibenzoylmethane?

The NOAEL (No Observed Adverse Effect Level) for Butyl Methoxydibenzoylmethane is 450 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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