Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
7 study endpoints found for Isostearyl Benzoate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=1200 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >8 other | oral | rat | oral | REACH |
| NOAEL | 2 other | oral | rat | oral | REACH |
| NOAEL | >8 other | oral | rat | oral | REACH |
| NOAEL | 2 other | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | dog | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | dog | oral | REACH |
Expert Verdict
Best-characterized ingredient. CIR concluded safe across baby products, eye makeup, lip products, sunscreens, and all skin and hair care categories.
Frequently Asked Questions
Is Isostearyl Benzoate safe in cosmetics?
Best-characterized ingredient. CIR concluded safe across baby products, eye makeup, lip products, sunscreens, and all skin and hair care categories. The EU classifies Isostearyl Benzoate as "permitted". Safety rating: EXCELLENT. 7 toxicological study endpoint(s) are available in our database.
Is Isostearyl Benzoate allowed in the EU?
Isostearyl Benzoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isostearyl Benzoate do in cosmetics?
Isostearyl Benzoate functions as: Skin conditioning agent — emollient, hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 68411-27-8.
What is the Margin of Safety for Isostearyl Benzoate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Isostearyl Benzoate?
The NOAEL (No Observed Adverse Effect Level) for Isostearyl Benzoate is >=1200 mg/kg bw/day based on a oral study via oral route in rat. A total of 7 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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