Is Isostearyl Benzoate safe in cosmetics?
Isostearyl Benzoate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
Isostearyl Benzoate
INCI: ISOSTEARYL BENZOATE
Isostearyl Benzoate (CAS 68411-27-8) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent — emollient, hair conditioning. NOAEL 1000 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 68411-27-8 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning agent — emollient, hair conditioning
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not restricted under 21 CFR
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isostearyl Benzoate.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Isostearyl Benzoate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =1000 mg/kg bw/day | oral | Rat | short-term | ToxValDB_ECHA_IUCLID |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Isostearyl Benzoate across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Emulsifier
Fragrance
Softener and conditioner
Solvent
Surfactant (surface active agent)
Wetting agent (non-aqueous)
Regulatory List Membership (2)
EU Regulated in Personal Care
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Isostearyl Benzoate.
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Isostearyl Benzoate by CAS number or substance name.
Studies
1
Lowest NOAEL
1000 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Chemical Function
Softener and conditioner
Emulsifier
Biocide
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
Europe; Personal care
Europe; Personal care
Europe; Personal care
consumer_product
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Isostearyl Benzoate allowed in the EU?
Isostearyl Benzoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isostearyl Benzoate do in cosmetics?
Isostearyl Benzoate functions as: Skin conditioning agent — emollient, hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 68411-27-8.
What is the NOAEL for Isostearyl Benzoate?
The NOAEL (No Observed Adverse Effect Level) for Isostearyl Benzoate is =1000 mg/kg bw/day based on a short-term study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.
Is Isostearyl Benzoate used outside cosmetics?
Isostearyl Benzoate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Isostearyl Benzoate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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