Is Cubosomes safe in cosmetics?
Cubosomes has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Active Ingredient
Cubosomes
INCI: GLYCERYL OLEATE
Cubosomes (CAS 9003-11-6) is a cosmetic active ingredient functioning as Advanced nanocarrier delivery systems for cosmetic actives. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 9003-11-6 →
Auto-generated CPSR Part A draft with source citations
Function
Advanced nanocarrier delivery systems for cosmetic actives
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cubosomes.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
9 property records from structured ingredient metadata.
comedogenicity_detail
{"comedogenicity_rating": "2", "irritancy_rating": "1", "skin_type_suitability": "dry,combination,normal", "acne_safe": "caution", "source": "Emulsifier"}
ecotoxicity
{"biodegradable": "yes", "biodegradation_days": "28-60", "bioaccumulative": "no", "aquatic_toxicity_level": "low", "coral_reef_safe": "yes", "marine_toxicity": "low aquatic toxicity", "freshwater_toxicity": "minimal impact", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environmental": "no", "pa…
emulsifier
{"cas_number": "25496-72-4", "ingredient_class": "W/O_emulsifier,co_emulsifier", "chemical_type": "glyceryl_ester", "HLB_value": "3.8", "HLB_required_for_oil_phase": "3-6", "emulsion_type_primary": "W/O", "droplet_size_typical_um": "5-10", "surface_tension_reduction_mN_m": "20-22", "interfacial_tension_reduction": "20-25", "foam_formation": "low", "liquid_crystal_formation": "low", "lamellar_phase…
emulsion_hlb
{"hlb_value": "3.5", "hlb_required_as_emulsifier": "yes", "emulsifier_type": "w_o", "critical_packing_parameter": "0.65-0.85", "emulsion_stabilization_mechanism": "steric_stabilization", "co_emulsifier_pairs": "oleyl_alcohol,sorbitan_oleate", "optimal_oil_phase_pct": "55-85", "optimal_water_phase_pct": "15-45", "electrolyte_tolerance": "moderate", "pH_emulsion_stability_range": "5.5-10.5", "viscos…
hair_care
{"hair_function": "conditioning", "hair_type_suitability": "all", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "moisture", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutral", "ker…
ph_stability
{"optimal_ph_min": "4.0", "optimal_ph_max": "9.0", "stable_ph_min": "3.5", "stable_ph_max": "10.0", "ph_dependent_function": "Natural O/W emulsifier", "formulation_note": "PEG-free emulsifier", "source": "Formulation literature"}
sensory
{"silky": "medium", "smooth, glides easily": "smooth, emulsifies", "dry-touch, non-greasy": "soft, smooth", "instant": "moderate", "low": "medium", "w/o": "o/w", "very-high": "high", "no": "no", "yes": "no", "light-diffusing": "luminous", "1.40": "1.47", "transparent": "translucent", "colorless": "amber", "excellent": "good", "light": "medium", "synthetic": "botanical"}
solubility_hlb
{"water_soluble": "no", "oil_soluble": "yes", "hlb_value": "5.0", "soluble_in": "oils, ethanol", "insoluble_in": "water", "log_p": "4.2", "appearance": "amber liquid", "source": "Oleon"}
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-streaking agent
Binder
Cleaning agent
Defoamer
Dispersing agent
Drier
Emulsifier
Filler
Humectant
Lubricating agent
Regulatory List Membership (2)
EPA Safer Chemical Ingredients List (SCIL)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Cubosomes.
Regulatory Flags
epa_safer_alternative
fda_food_additive
Chemical Function
Surfactant (surface active agent)
Solvent
Regulatory Lists
fracking; water
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
inert_ingredient; non_food_use; Pesticides
pharmaceutical
active_ingredient; animal_products; Europe; pharmaceutical; residue
SCIL (9/2019)
Canada; pharmaceutical
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
inert_ingredient; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Cubosomes allowed in the EU?
Cubosomes EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cubosomes do in cosmetics?
Cubosomes functions as: Advanced nanocarrier delivery systems for cosmetic actives. It is classified as a Active Ingredient in our database. CAS number: 9003-11-6.
Compliance Tools
Check Cubosomes compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Acetyl Tetrapeptide-5
Excellent
Same category
Anti-edema peptide for periorbital ar...
Activated Charcoal
Excellent
Same category
Adsorbent; skin cleanser; pore-cleans...
Adenosine
Excellent
Same category
Skin-conditioning agent, anti-aging, ...
Allantoin
Excellent
Same category
Skin conditioner, keratolytic, anti-i...
Alpha-Glucan Oligosaccharide
Excellent
Same category
prebiotic, skin-conditioning
Ascophyllum Nodosum Extract
Excellent
Same category
Skin Brightening, Tyrosinase Inhibito...
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
AMMONIUM POLYACRYLATE
Good
Chemical family
Film Forming, Light Stabilizer, Surfa...
Acrylates Crosspolymer
Good
Chemical family
Absorbent, Film Former, Viscosity Con...
Acrylonitrile/Butadiene/Styrene Copolymer
Moderate
Chemical family
Film forming
Is Cubosomes in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Cubosomes in your formulation.