DIHYDROXYINDOLE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Toxicological Studies
2 study endpoints found for DIHYDROXYINDOLE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 3 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| LOAEL | 10 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
DIHYDROXYINDOLE is listed in the EU CosIng database with functions: Hair Dyeing It is prohibited under EU Cosmetics Regulation (Annex II).
Regulatory Flags
Frequently Asked Questions
Is DIHYDROXYINDOLE safe in cosmetics?
DIHYDROXYINDOLE is listed in the EU CosIng database with functions: Hair Dyeing It is prohibited under EU Cosmetics Regulation (Annex II). The EU classifies DIHYDROXYINDOLE as "Prohibited". Safety rating: POOR. 2 toxicological study endpoint(s) are available in our database.
Is DIHYDROXYINDOLE allowed in the EU?
DIHYDROXYINDOLE EU regulatory status: Prohibited. Maximum allowed concentration: Annex III/207. This is based on EU Regulation 1223/2009 and its amendments.
What does DIHYDROXYINDOLE do in cosmetics?
DIHYDROXYINDOLE functions as: Hair Dyeing. It is classified as a cosmetic ingredient in our database. CAS number: 3131-52-0.
What is the NOAEL for DIHYDROXYINDOLE?
The NOAEL (No Observed Adverse Effect Level) for DIHYDROXYINDOLE is 3 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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