Is Diisobutyl Adipate safe in cosmetics?
Diisobutyl Adipate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Diisobutyl Adipate
INCI: DIISOBUTYL ADIPATE
Diisobutyl Adipate (CAS 141-04-8) is a cosmetic cosmetic ingredient functioning as Emollient / skin conditioning agent; also evaluated as a food-grade flavouring. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 141-04-8 →
Auto-generated CPSR Part A draft with source citations
Function
Emollient / skin conditioning agent; also evaluated as a food-grade flavouring agent
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
bis(2-methylpropyl) hexanedioate
InChIKey
RDOFJDLLWVCMRU-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — JECFA evaluation: no safety concern at current levels of intake (2010)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Diisobutyl Adipate.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Diisobutyl Adipate.
Regulatory Flags
endocrine_disruptor
epa_safer_alternative
ifra_fragrance
fda_food_additive
jecfa_safe
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3184260
Frequently Asked Questions
Is Diisobutyl Adipate allowed in the EU?
Diisobutyl Adipate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diisobutyl Adipate do in cosmetics?
Diisobutyl Adipate functions as: Emollient / skin conditioning agent; also evaluated as a food-grade flavouring agent. It is classified as a cosmetic ingredient in our database. CAS number: 141-04-8.
Is Diisobutyl Adipate used outside cosmetics?
Diisobutyl Adipate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Diisobutyl Adipate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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