Moderate UV Filter / Sunscreen Sensitization Data

Drometrizole Trisiloxane (Mexoryl XL)

INCI: DROMETRIZOLE TRISILOXANE

CAS Number
155633-54-8
Function
UV Filter
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not GRAS; restricted use in sunscreen products

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Drometrizole Trisiloxane (Mexoryl XL) based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
other
EU Allergen Listed
no
Patch Test Positive Rate
0.1%
Cross-reactivity Group
none
Reaction Type
contact-dermatitis

Source: SCCS

Expert Verdict

UV filter approved in EU; use with caution and adhere to concentration limits.

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Concern Level: Moderate

Regulatory Flags

eu_cosing_listed

Frequently Asked Questions

Is Drometrizole Trisiloxane (Mexoryl XL) safe in cosmetics?

UV filter approved in EU; use with caution and adhere to concentration limits. The EU classifies Drometrizole Trisiloxane (Mexoryl XL) as "permitted". Safety rating: MODERATE.

Is Drometrizole Trisiloxane (Mexoryl XL) allowed in the EU?

Drometrizole Trisiloxane (Mexoryl XL) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Drometrizole Trisiloxane (Mexoryl XL) do in cosmetics?

Drometrizole Trisiloxane (Mexoryl XL) functions as: UV Filter. It is classified as a UV Filter / Sunscreen in our database. CAS number: 155633-54-8.

What is the Margin of Safety for Drometrizole Trisiloxane (Mexoryl XL)?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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