Regulatory Status
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Safety Data
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Expert Verdict
GHS: H315 (skin irritation), H319 (eye irritation), H335/H336 (respiratory irritation/narcosis); EFSA genotoxicity finding for hydroxyanthracene derivatives; NTP equivocal carcinogenicity evidence in F344/N rats; phototoxicity potential — aloe-emodin accelerated UV-induced melanoma in mice; mutagenicity data inconclusive; no SCCS opinion specific to cosmetic use; EU CMR classification pathway could trigger Annex II listing
Regulatory Flags
Frequently Asked Questions
Is Emodin safe in cosmetics?
GHS: H315 (skin irritation), H319 (eye irritation), H335/H336 (respiratory irritation/narcosis); EFSA genotoxicity finding for hydroxyanthracene derivatives; NTP equivocal carcinogenicity evidence in F344/N rats; phototoxicity potential — aloe-emodin accelerated UV-induced melanoma in mice; mutagenicity data inconclusive; no SCCS opinion specific to cosmetic use; EU CMR classification pathway could trigger Annex II listing The EU classifies Emodin as "prohibited". Safety rating: POOR.
Is Emodin allowed in the EU?
Emodin EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Emodin do in cosmetics?
Emodin functions as: Skin conditioning (anthraquinone derivative found in rhubarb, aloe, cascara). It is classified as a cosmetic ingredient in our database. CAS number: 518-82-1 [^1_4].
What is the Margin of Safety for Emodin?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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