Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Sensitization Profile
Contact sensitization data for Hexamethylindanopyran based on clinical patch test studies and IFRA standards.
Source: EU 2023/1545; SCCS/1459/11
Expert Verdict
HIGH PRIORITY. France's CLH proposal for reproductive toxicity (Cat. 1B) and endocrine disruption could result in Annex II prohibition under Article 15 of Reg. 1223/2009. Environmental persistence and bioaccumulation documented. CPSR assessors should monitor ECHA RAC opinion timeline. If classified CMR 1B, Article 15 requires explicit SCCS safety opinion to continue use.
Regulatory Flags
Frequently Asked Questions
Is Hexamethylindanopyran safe in cosmetics?
HIGH PRIORITY. France's CLH proposal for reproductive toxicity (Cat. 1B) and endocrine disruption could result in Annex II prohibition under Article 15 of Reg. 1223/2009. Environmental persistence and bioaccumulation documented. CPSR assessors should monitor ECHA RAC opinion timeline. If classified CMR 1B, Article 15 requires explicit SCCS safety opinion to continue use. The EU classifies Hexamethylindanopyran as "prohibited". Safety rating: POOR.
Is Hexamethylindanopyran allowed in the EU?
Hexamethylindanopyran EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexamethylindanopyran do in cosmetics?
Hexamethylindanopyran functions as: Perfuming / fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 1222-05-5 (also known as Galaxolide® / HHCB).
What is the Margin of Safety for Hexamethylindanopyran?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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