Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Sensitization Profile
Contact sensitization data for Galaxolide based on clinical patch test studies and IFRA standards.
Source: EU 2023/1545; SCCS/1459/11
Expert Verdict
Widely used synthetic musk with moderate bioaccumulation in aquatic organisms and environmental persistence; ubiquitously detected in human blood, breast milk, and aquatic organisms; combined exposure studies at real-world concentrations show toxicological effects, driving EU REACH and EPA regulatory scrutiny. Use with caution and consider macrocyclic replacements.
Regulatory Flags
Frequently Asked Questions
Is Galaxolide safe in cosmetics?
Widely used synthetic musk with moderate bioaccumulation in aquatic organisms and environmental persistence; ubiquitously detected in human blood, breast milk, and aquatic organisms; combined exposure studies at real-world concentrations show toxicological effects, driving EU REACH and EPA regulatory scrutiny. Use with caution and consider macrocyclic replacements. The EU classifies Galaxolide as "restricted". Safety rating: MODERATE.
Is Galaxolide allowed in the EU?
Galaxolide EU regulatory status: restricted. Maximum allowed concentration: Labeling required above 10 ppm leave-on / 100 ppm rinse-off. This is based on EU Regulation 1223/2009 and its amendments.
What does Galaxolide do in cosmetics?
Galaxolide functions as: Fragrance fixative (polycyclic synthetic musk, sweet floral-musky scent). It is classified as a Fragrance in our database. CAS number: 1222-05-5.
What is the Margin of Safety for Galaxolide?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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