Is Hexapeptide-11 (Myristoyl Hexapeptide-16) safe in cosmetics?
Hexapeptide-11 (Myristoyl Hexapeptide-16) has a safety rating of "MODERATE" in our database. EU status: permitted. US status: restricted.
Hexapeptide-11 (Myristoyl Hexapeptide-16)
INCI: HEXAPEPTIDE-11
Hexapeptide-11 (Myristoyl Hexapeptide-16) (CAS 161258-30-6) is a cosmetic active ingredient functioning as Peptide / Anti-aging active. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 161258-30-6 →
Function
Peptide / Anti-aging active
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
CIR Safety Assessment: No dedicated report. OTC drug classification applies.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexapeptide-11 (Myristoyl Hexapeptide-16).
Calculate MoS for your specific formulation with the MoS Calculator.
Dermal Penetration Profile
Skin absorption and penetration characteristics of Hexapeptide-11 (Myristoyl Hexapeptide-16), relevant to systemic exposure and MoS calculations.
Absorption %
1-3%
Penetration Level
surface
Penetration Depth
stratum corneum
Molecular Weight
673.8 Da
Log P
-0.8
Systemic Absorption
minimal
Topical Bioavailability
0.5-2%
Safety Margin Factor
minimal
Vehicle Dependent
Yes — absorption varies by formulation
Source: Cosmetic Science
Editorial summary
Preliminary editorial summary for Hexapeptide-11 (Myristoyl Hexapeptide-16) — not a computed safety verdict. See the sourced toxicological data above.
Frequently Asked Questions
Is Hexapeptide-11 (Myristoyl Hexapeptide-16) allowed in the EU?
Hexapeptide-11 (Myristoyl Hexapeptide-16) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexapeptide-11 (Myristoyl Hexapeptide-16) do in cosmetics?
Hexapeptide-11 (Myristoyl Hexapeptide-16) functions as: Peptide / Anti-aging active. It is classified as a Active Ingredient in our database. CAS number: 161258-30-6.
Compliance Tools
Check Hexapeptide-11 (Myristoyl Hexapeptide-16) compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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