Poor Cosmetic Ingredient GHS Classified

Hexene (1-Hexene)

INCI: HEXENE

CAS Number
592-41-6
Function
Fragrance component (IFRA listed) or solvent/process residual
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status restricted
US Notes Not specifically restricted under 21 CFR for cosmetics; no CIR review; general safety falls under FDA's adulteration provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is mildly irritating to the eyes and respiratory tract. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis. Exposure at high levels could cause lowering of consciousness.
Long-term Exposure Effects
The substance defats the skin, which may cause dryness or cracking.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its vapour.

Expert Verdict

Highly flammable (flash point −12.2 °C) with aspiration hazard (H304). Acts as defatting agent on prolonged/repeated skin contact. Not a standard cosmetic ingredient; presence in formulation should be justified. IFRA environmental standards apply to fragrance use.

⚠️
Concern Level: High

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is Hexene (1-Hexene) safe in cosmetics?

Highly flammable (flash point −12.2 °C) with aspiration hazard (H304). Acts as defatting agent on prolonged/repeated skin contact. Not a standard cosmetic ingredient; presence in formulation should be justified. IFRA environmental standards apply to fragrance use. The EU classifies Hexene (1-Hexene) as "restricted". Safety rating: POOR.

Is Hexene (1-Hexene) allowed in the EU?

Hexene (1-Hexene) EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexene (1-Hexene) do in cosmetics?

Hexene (1-Hexene) functions as: Fragrance component (IFRA listed) or solvent/process residual. It is classified as a cosmetic ingredient in our database. CAS number: 592-41-6.

What is the Margin of Safety for Hexene (1-Hexene)?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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