Moderate Cosmetic Ingredient GHS Classified

METHYLENE DIPHENYL DIISOCYANATE

CAS Number
101-68-8
Function
Not Reported
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status Restricted
EU Max Conc. II/1533
🇺🇸 US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
Lachrymation. The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the lungs. This may result in impaired functions.
Long-term Exposure Effects
Repeated or prolonged contact may cause skin sensitization. Repeated or prolonged inhalation may cause asthma. See Notes.
Routes of Exposure
The substance can be absorbed into the body by inhalation.

Expert Verdict

METHYLENE DIPHENYL DIISOCYANATE is listed in the EU CosIng database with functions: Not Reported It is restricted under EU Cosmetics Regulation. Restriction: II/1533.

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Concern Level: Medium

Regulatory Flags

cosing-sourced eu-restricted needs-enrichment

Frequently Asked Questions

Is METHYLENE DIPHENYL DIISOCYANATE safe in cosmetics?

METHYLENE DIPHENYL DIISOCYANATE is listed in the EU CosIng database with functions: Not Reported It is restricted under EU Cosmetics Regulation. Restriction: II/1533. The EU classifies METHYLENE DIPHENYL DIISOCYANATE as "Restricted". Safety rating: MODERATE.

Is METHYLENE DIPHENYL DIISOCYANATE allowed in the EU?

METHYLENE DIPHENYL DIISOCYANATE EU regulatory status: Restricted. Maximum allowed concentration: II/1533. This is based on EU Regulation 1223/2009 and its amendments.

What does METHYLENE DIPHENYL DIISOCYANATE do in cosmetics?

METHYLENE DIPHENYL DIISOCYANATE functions as: Not Reported. It is classified as a cosmetic ingredient in our database. CAS number: 101-68-8.

Compliance Tools

Check METHYLENE DIPHENYL DIISOCYANATE compliance across multiple jurisdictions:

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